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Welcome to the 2025 RMACC HPC Symposium!
Type: Technical Talk clear filter
Tuesday, May 20
 

2:30pm MDT

Gaining file system intelligence and operational efficiency with the VAST data platform
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
As the shape and demands of large scale computing environments have evolved, so have the needs of those who are responsible for keeping them in tip top shape. HPC administrators are challenged with knowing what the data on their system looks like, who’s doing what to the data and tracking jobs on the system. In this talk we’ll cover how the VAST data platform’s powerful structured data component and analytics makes these tasks easy.
Speakers
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
Room 206

2:30pm MDT

Regulatory Interpretation for STEM Majors
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
      Scientists, Engineers, and Technologists live in a world of data, methodical analysis, and measurable outcomes. Scientific research is increasingly being held to regulatory standards that are vague and ambiguous. How can the scientific community understand and adapt to this shifting regulatory landscape?
Speakers
SK

Silas Korb

University of Colorado Boulder
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
Wolf Law Courtroom

2:30pm MDT

Security & Compliance in Scientific Data Management: Ensuring Integrity and Immutability
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
In today's research landscape, protecting scientific data from tampering and unauthorized access and adhering to compliance driven security measures is critical. Effective data management solutions must ensure integrity and immutability while enabling secure collaboration across institutions and research labs. By implementing policy-driven access controls, encryption, and compliance-driven security measures, organizations can safeguard sensitive research data against breaches and unauthorized modifications. This approach not only enhances data security but also ensures adherence to regulatory frameworks, fostering trust in the integrity and reproducibility of scientific discoveries while enabling secure, compliant data sharing.
Speakers
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
Room 207

2:30pm MDT

Supporting quantum-inspired optimization on a university compute cluster
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
As quantum computing continues to develop, quantum-inspired algorithms are emerging as powerful tools that leverage quantum principles on classical hardware to solve complex optimization problems. Universities are uniquely positioned to support research in this area by enabling access to compute resources tailored to the specific demands of quantum-inspired techniques. This session explores the strategies, challenges, advantages and best practices in supporting quantum-inspired optimization workloads on a university compute cluster. We will discuss software frameworks (such as pyqubo, Matlab tools, D-Wave's Ocean tools and NEC's Vector Annealing software) and specialized hardware considerations. The session will also highlight case studies from active research projects.
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
Room 205

2:30pm MDT

Using RMACC for optimization problems in quantum computing
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
In this presentation, I will describe our group’s efforts in leveraging high-performance computing (HPC), particularly the RMACC cluster, to tackle computationally intensive optimization problems in quantum computing. In our first case study, we address a quantum optimal control problem that requires fine-tuning numerous pulse parameters to optimize the performance of a quantum gate on a superconducting quantum computer. This optimization is carried out through large-scale parallel executions of a stochastic gradient descent (SGD) algorithm with multiple random seeds on RMACC. In the second case, we apply RMACC to solve a maximum likelihood estimation (MLE) problem for learning structured quantum states from synthetic measurement data. Our approach involves generating a vast number of measurement samples in parallel using a novel autoregressive method and subsequently performing MLE via SGD. In both applications, our approach yields near-optimal results that align with theoretical upper bounds, demonstrating that RMACC could provide an efficient, cost-effective HPC solution for state-of-the art quantum research in local institutions.
Speakers
Tuesday May 20, 2025 2:30pm - 3:00pm MDT
Room 204

3:15pm MDT

Dell Session
Tuesday May 20, 2025 3:15pm - 4:15pm MDT
Tuesday May 20, 2025 3:15pm - 4:15pm MDT
Room 206

4:30pm MDT

Software sustainability and green initiatives
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Speakers
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Room 205

4:30pm MDT

Supercharging HPC productivity with projectEureka-Omnibond
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
We will show how projectEureka can enable increased
researcher productivity by providing an interactive research and data
science platform. projectEureka provides a convenient and
easy-to-use web interface for researchers to access HPC resources by
bridging data and compute in the cloud and on
premises through Kubernetes.
Speakers
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Room 207

4:30pm MDT

Supercharging HPC with IQM Quantum Computers
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Quantum computers (QC) can significantly enhance high-performance computing (HPC) as accelerators with unique capabilities for solving challenging chemistry, materials science, and optimization problems. Hybrid HPC+QC system offers unique advantages that neither classical nor quantum simulations can achieve independently. Our collaboration between IQM, a leading quantum hardware company, and a premier HPC center has demonstrated practical integration of quantum and classical resources. We present the details of our technical implementation, including hardware and software requirements, networking, and selection of the appropriate space to house the quantum computer, as well as initial scientific results coming out of that collaboration. We also discuss how QC can be integrated with minimal disruption into HPC workflows and the benefits of on-prem QC. ​​​​
Speakers
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Room 205

4:30pm MDT

SysAdmin Lightning talks
Tuesday May 20, 2025 4:30pm - 5:00pm MDT

 Microsoft Windows through Open OnDemand by Paige Despain
7lbd is an innovative open-source project that simplifies Windows deployment in HPC environments by treating Windows as an application within Open OnDemand. The solution eliminates traditional infrastructure complexities by using technologies like Apache Guacamole, network namespaces, and a simplified Windows VM configuration to provide secure, isolated Windows desktops across computing clusters. This solution simplifies Windows to a level that even Linux systems administrators will find easy to maintain while maintaining robust security and accessibility, no AD required.

An Approach to SLURM Configuration Verification  by Kyle Reinholt
Ensuring the correctness of Slurm configurations is crucial for maintaining high-performance computing (HPC) environments, but validating these configurations effectively remains a challenge. In this lightning talk, we will explore existing approaches to Slurm configuration verification, including manual checks, custom scripts, and automated validation tools. While these methods offer some benefits, they often fall short in scalability and flexibility. The talk will then shift focus to exploring potential solutions for improving configuration verification, discussing innovative strategies, and tools that could streamline the process, reduce errors, and enhance cluster reliability.

Speakers
KR

Kyle Reinholt

University of Colorado Boulder
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Wolf Law Courtroom

4:30pm MDT

Watching Electrons Move
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Since their discovery in the late 1800’s, electrons have been a constant source of study for scientists. Their properties and behavior have been studied and harnessed to produce some of the greatest inventions of the past century, including electron microscopes and particle accelerators. However one fundamental question about their behavior still remains: how do electrons move inside atoms and molecules?
Electron motion within atoms has proved difficult to study due to the incredibly short timescale it occurs on (the attosecond timescale, or 10-18 seconds). One method of capturing electron motion is to use very short laser pulses to take a series of snapshots of the system. This requires laser pulses shorter than the duration of the dynamics we want to observe (similar to using a short flash on a camera to obtain an image of a fast-moving object). The means to do this have only become possible in the past decade with the advent of new ultrashort (less than 100 as) lasers, which have become feasible due to a process called high‐harmonic generation (HHG).
However, these ultrashort lasers are difficult to produce and characterize experimentally, so theoretical and computational methods are often used in the field of attoscience. These methods are also not without their limitations – modelling the correlated behavior of electrons requires significant computing resources, and so High-Performance Computing (HPC) resources are often used to perform these calculations. In this seminar I will present recent results obtained using R-Matrix with Time-dependence (RMT) method calculations performed on national HPC resources, firstly to treat high-harmonic generation in two-color laser fields, and then on applications of the attosecond pulses generated during the HHG process to measure ionization delays.
Speakers
KH

Kathryn Hamilton

University of Colorado Denver
Tuesday May 20, 2025 4:30pm - 5:00pm MDT
Room 206
 
Wednesday, May 21
 

10:30am MDT

Advancing Research Through AWS AI Infrastructure: A Comprehensive Overview with Live Demos
Wednesday May 21, 2025 10:30am - 11:00am MDT
This presentation explores AWS latest developments in AI infrastructure and tools designed specifically for research communities. We'll examine the transformation of SageMaker Studio, the introduction of the Build on Trainium program, and the strategic positioning of Amazon Bedrock alongside SageMaker AI. This session will highlight how these integrated solutions address the evolving needs of researchers, from individual projects to large-scale collaborative efforts. Live demonstrations of SageMaker Studio and Bedrock API integration will showcase the practical application of these tools in research environments.
Speakers
Wednesday May 21, 2025 10:30am - 11:00am MDT
Room 204

10:30am MDT

AI enabled protein interaction modeling
Wednesday May 21, 2025 10:30am - 11:00am MDT
AI assisted protein interaction modeling, pioneered by AlphaFold and RosettaFold, has become more diverse both with respect to the programs that do it, and how users run these programs. In this talk, we will cover the programs that are supported at the University of Utah, namely Alphafold2, Alphafold3, Colabfold, Boltz1, RFDiffusion and other tools from the Baker lab, the choices we have made with their deployment, and our experiences with using them. With respect to the ways to run, we will go over the standard SLURM scripts to run Alphafold in two stages (CPU only MSA search, GPU accelerated inference), use Colabfold server for faster MSA search, and using Google Colab running on compute nodes for interactive modeling in a notebook interface. Attendees should leave this talk with ideas how to set up and support these tools and contacts to UofU staff for further questions.
Speakers
Wednesday May 21, 2025 10:30am - 11:00am MDT
Room 206

10:30am MDT

Chemistry beyond exact solutions on a Quantum-Centric Supercomputer
Wednesday May 21, 2025 10:30am - 11:00am MDT
A universal quantum computer can be used as a simulator capable of predicting properties of diverse quantum systems. Electronic structure problems in chemistry offer practical use cases around the hundred-qubit mark. This appears promising since current quantum processors have reached these sizes. However, mapping these use cases onto quantum computers yields deep circuits, and for pre-fault-tolerant quantum processors, the large number of measurements to estimate molecular energies leads to prohibitive runtimes. As a result, realistic chemistry is out of reach of current quantum computers in isolation. A natural question is whether classical distributed computation can relieve quantum processors from parsing all but a core, intrinsically quantum component of a chemistry workflow. Here, we incorporate quantum computations of chemistry in a quantum-centric supercomputing architecture, using up to 6400 nodes of the supercomputer Fugaku to assist a quantum computer with a Heron superconducting processor. We simulate the N2 triple bond breaking in a correlation-consistent cc-pVDZ basis set, and the active-space electronic structure of [2Fe-2S] and [4Fe-4S] clusters, using 58, 45 and 77 qubits respectively, with quantum circuits of up to 10570 (3590 2-qubit) quantum gates. We obtain our results using a class of quantum circuits that approximates molecular eigenstates, and a hybrid estimator. The estimator processes quantum samples, produces upper bounds to the ground-state energy and wavefunctions supported on a polynomial number of states. This guarantees an unconditional quality metric for quantum advantage, certifiable by classical computers at polynomial cost. For current error rates, our results show that classical distributed computing coupled to quantum computers can produce good approximate solutions for practical problems beyond sizes amenable to exact diagonalization.
Speakers
Wednesday May 21, 2025 10:30am - 11:00am MDT
Room 207

10:30am MDT

Curating and Publishing Big Datasets Using CU Boulder High Performance Computing Infrastructure
Wednesday May 21, 2025 10:30am - 11:00am MDT
Publication of research datasets is now a requirement of most funding agencies and journals. Data curation is the process of ensuring that these datasets are findable, accessible, and usable. In the era of Big Data, the generation of datasets with sizes on the order of 100s of gigabytes and larger is increasingly common. Such large datasets create challenges for both the curation and publishing of data as they often cannot be accessed on standard computer hardware or hosted in traditional online repositories. This presentation provides an overview of a collaborative process between the CU Boulder Libraries and CU Boulder Research Computing in which high-performance computing infrastructure is used to curate and publish gigabyte- and terabyte-scale datasets in a manner that makes them accessible to the research community.
Wednesday May 21, 2025 10:30am - 11:00am MDT
Wolf Law Courtroom

10:30am MDT

Front Range GigaPoP (FRGP) Research and Education Network (REN) Connecting Colorado Cyber-Infrastructure (CI)
Wednesday May 21, 2025 10:30am - 11:00am MDT
The Front Range GigaPop (FRGP) is a longstanding network in Colorado that connects universities, government agencies, and schools to Internet2, peering exchanges, and the broader Internet through shared fiber-optic, routed and packet-switched infrastructure.

A recent NSF grant is funding the expansion of FRGP to the Western Slope, providing 10Gbps connections to Mesa State Metropolitan State University in Grand Junction (MSU), Western Colorado University in Gunnison (WSU), and the Rocky Mountain Biological Laboratory in Gothic (RMBL).

This presentation will highlight FRGP’s services and showcase its role in advancing cyberinfrastructure (CI) across the region.
Speakers
Wednesday May 21, 2025 10:30am - 11:00am MDT
Room 205

11:15am MDT

DDN
Wednesday May 21, 2025 11:15am - 12:15pm MDT
Speakers
Wednesday May 21, 2025 11:15am - 12:15pm MDT
Room 204

11:15am MDT

GenomEX 2.0
Wednesday May 21, 2025 11:15am - 12:15pm MDT
The University of North Dakota (UND) Genomics Core has launched GenomEX 2.0, the first comprehensive and user-friendly bioinformatics platform powered by Oracle Cloud Infrastructure. This innovative platform enables biologists to seamlessly install over 13,000 bioinformatics tools, generate and execute custom code or command lines, and receive real-time guidance from an AI-based bioinformatics assistant—all through intuitive, one-click processes.
To support the computing requirements for any bioinformatics tools, the platform is powered by the Oracle Cloud Infrastructure that provides fully secured (built-in security features and compliance certifications), personalized (adjustable CPU/GPU numbers & memory/storage capacity), dedicated (resources available 24/7 without any queue) and customizable (users have administrator rights) cloud-based high-performance computing environments at unbeatable pricing.
Through the combined expertise of the UND Genomics Core and Oracle, GenomEX 2.0 emerges as a powerful and unique bioinformatics platform, providing every biologist with the freedom to explore biological data independently, regardless of their coding proficiency.
Wednesday May 21, 2025 11:15am - 12:15pm MDT
Room 207

3:00pm MDT

Accelerating Research Outcomes with GenAI and HPC
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
How can your research teams leverage and apply high performance computing to supercharge your own efforts for research momentum to get to outcomes faster?

When generative AI (GenAI) was first introduced, our AI team identified the proposal process as a top use case for GenAI augmentation. Our AI experts set out to build a GenAI-powered application to help the Proposal team streamline the complex RFP process. The goal was to build an intelligent assistant that accelerated RFP qualification, helped proposal managers quickly grasp the key aspects of lengthy RFP document sets, and searched multiple databases for relevant information to automatically generate a quality response draft.

The now successful internally developed GenAI solution significantly shortens the Proposal team's response time, allowing them to answer to more proposals and spend more time on response quality and win strategies. This use case will be expanded to support the whole process of winning customer engagement, from drafting Statements of Work (SOWs) to proposal PowerPoint presentations.

In the spirit of exploring the art of the possible, we will share a live demo of capability in use for creating proposals and responses for project funding.
Speakers
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Room 207

3:00pm MDT

Advancing Research with AWS: Compliance, Computing, and Connectivity
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
This presentation explores AWS comprehensive solutions for the research community, addressing three critical challenges: meeting evolving compliance requirements like the new NIH NIST 800-171 standards, delivering scalable high-performance computing, and simplifying data management. We'll examine how the AWS Secure Research Environment (SRE) addresses complex security needs, compare managed AWS ParallelCluster Service with self-managed options, and showcase tools like the Globus S3 Connector for streamlined data handling. Join us to discover how AWS empowers researchers to focus on innovation while maintaining security, performance, and efficiency at scale.
Speakers
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Room 206

3:00pm MDT

HPC Skills and Opportunities Development in RMACC
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
This talk shares the story of an NSF-funded experiential learning opportunity for undergraduate and graduate students at RMACC institutions. Students developed practical skills in HPC system administration by learning from and shadowing CU Boulder Research Computing staff. A total of 17 students participated across two in-person experiences and took part in various aspects of system design, deployment, and teardown.
Speakers
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Wolf Law Courtroom

3:00pm MDT

Introduction to Quantinuum Compute Products
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Come and learn more about Quantinuum and their compute offerings
Speakers
JS

Josh Savory

Quantinuum
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Room 205

3:00pm MDT

Managing RCD Professionals
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Perhaps management is in your future. Or you have recently been cast in that role and you would appreciate some suggestions. Attend this session to collect some useful references, and discuss the importance of our role and maximizing the impact of our teams
Speakers
Wednesday May 21, 2025 3:00pm - 3:30pm MDT
Room 204

3:45pm MDT

A Practical Approach for Evaluating the Effectiveness of NSF NCAR's HPC Environment
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
In the presentation, we would share info on topics such as metrics, our user survey, and some other approaches. As part of the talk, we would like to engender a discussion and exchange of info about what other sites do to measure the effectiveness of their HPC environments.
Speakers
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
Room 204

3:45pm MDT

Data Lifecycle Management in HPC – Automating Tiered Storage & Archival Strategies- Arcitecta
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
Managing data at scale in high-performance computing (HPC) environments requires efficient storage and retrieval strategies. Automated tiered storage solutions enable seamless migration of aged data to lower-cost archival tiers while maintaining accessibility. Enriched metadata—spanning tagging, search, discovery, and data provenance—enhances data usability and long-term value. This approach not only optimizes storage costs but also empowers researchers with better data discovery and reuse. Real-world HPC use cases demonstrate how metadata-driven workflows streamline research, ensuring that critical datasets remain accessible and actionable over time.
Speakers
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
Room 206

3:45pm MDT

Optimizing HPC and AI Infrastructure with Standard Linux and Advanced Storage Architectures
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
AI workloads present new challenges for traditional HPC architectures, particularly as compute demands outpace I/O performance, power constraints tighten, and budgets remain stretched. The need for high-throughput, low-latency data access at extreme scale is forcing a re-evaluation of storage architectures to maximize efficiency without incurring unsustainable costs.

This session will explore how standard Linux and open storage technologies enable AI and HPC workloads to achieve parallel file system performance on commodity hardware—without requiring specialized infrastructure. Topics include:
• Scaling AI Storage with Standard Linux: Leveraging NFSv4.2 advancements, including pNFS and FlexFiles, to enable parallel I/O at extreme scales.
• Next-Generation SSD Integration: How embedding parallel file system capabilities into SSDs reduces data movement overhead while maximizing power efficiency.
• Accelerating AI with Localized Storage on GPU/CPU Servers: Techniques to optimize checkpointing and ephemeral data storage, reducing I/O bottlenecks and overall infrastructure costs.

The session will feature real-world examples of how these innovations are being deployed today to drive high-performance AI workloads while addressing power and cost constraints.
Speakers
MP

Molly Presley

Head of Global Marketing - Hammerspace & Host of Data Unchained Podcast., Hammerspace
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
Room 205

3:45pm MDT

The AI Power Crunch – Storage Solutions that Reduce Power Footprint
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
This presentation highlights the rapid growth in Field Effect Transistor (FET) technology, with modern GPUs containing over 200 billion transistors each. As transistor counts soar, so does power consumption—Nvidia’s shipped GPUs alone consumed over 14 TWh in 2023. With global data center energy demands projected to triple, the presentation advocates for transitioning data from power-hungry disk storage to more energy-efficient systems. This shift offers significant power savings, lower carbon emissions, and cost reductions—providing a scalable path to support future computing growth without overloading existing power infrastructure.
Speakers
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
Room 207

3:45pm MDT

The Practicalities of Quantum-Centric High-Performance Computing
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
This workshop will act as a continuation of last year's presentation and discussion on quantum-centric high-performance computing (QCHPC). We will again look at realistic instances in the current noisy intermediate-scale quantum (NISQ) -era, how these (and other use cases) might scale with quantum hardware, and strategies for integration of quantum resources with HPC. We will consider approaches to putting these hybrid paradigms into practice; Symposium members are encouraged to contribute efforts made by their HPC departments, both from emulation/simulation and hardware integration perspectives. The workshop is intended as a space to explore ideas, share experiences and gather knowledge to advance quantum-centric HPC in our region.
Speakers
Wednesday May 21, 2025 3:45pm - 4:15pm MDT
Wolf Law Courtroom

4:30pm MDT

Fuzzball: a new paradigm for accessing HPC resources
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Fuzzball, from CIQ, is a new way to access and manage HPC resources, whether they're on-prem, in the cloud, or both. Fuzzball is API-driven, container-forward, and offers co-equal web and command-line interfaces. With its well-defined workflow definitions, including first-class support for container management and data ingress and egress, Fuzzball workflows are portable to both local clusters and cloud resources.

In this session we will give an overview of Fuzzball, describe some of its potential use cases, and highlight some of its unique features, including a visual workflow builder, portable workflows, and its templated workflow catalog.
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Room 207

4:30pm MDT

Launching a Public Cloud Small State University: Lessons from the First Six Months
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
As research demands grow and infrastructure ages, some institutions are turning to the public cloud to supplement or replace traditional on-prem systems. This talk shares the journey of launching a public cloud pilot for research computing at a small state university. We’ll explore the drivers behind the shift—including scalability, agility, and cost transparency—and walk through key decisions, from selecting a cloud provider to identifying test users. Drawing from real-world experience six months post-launch, we’ll cover what’s worked, what’s surprised us, and what we’re planning next. Attendees will leave with a practical roadmap and lessons learned to guide their own cloud adoption efforts—whether starting small or scaling up.
Speakers
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Wolf Law Courtroom

4:30pm MDT

NVIDIA CUDA-Q Overview
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
CUDA-Q is an open-source quantum development platform orchestrating the hardware and software needed to run useful, large-scale quantum computing applications. The platform’s hybrid programming model allows computation on GPU, CPU, and QPU resources in tandem from within a single quantum program. CUDA-Q is “qubit-agnostic”—seamlessly integrating with all QPUs and qubit modalities and offering GPU-accelerated simulations when adequate quantum hardware is not available.

CUDA-Q extends simulation tools far beyond the NISQ-era—charting a course to large-scale, error-corrected quantum supercomputing.
Speakers
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Room 205

4:30pm MDT

Supporting FPGA applications on a university compute cluster
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Field-Programmable Gate Arrays (FPGAs) are gaining traction in research for their ability to deliver high-performance, energy-efficient computing across a range of domains—from machine learning and data analytics to signal processing and scientific simulations. However, integrating FPGA workflows into a shared university compute cluster presents unique challenges in terms of hardware management, toolchain support and user access. This session will explore the practical aspects of supporting FPGA applications in a multi-user academic environment. We will cover available FPGA platforms, commonly used development workflows (such as Xilinx Vivado and Vitis, Intel Quartus and OpenCL, and HLS), and the architectural and administrative considerations for cluster integration. Real-world use cases will illustrate how researchers and academics are leveraging FPGAs, and we’ll share lessons learned in enabling productive FPGA development. Attendees will gain insight into both the technical setup and the support models that foster a thriving FPGA user community on campus.
Speakers
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Room 204

4:30pm MDT

The Metadata Revolution: Accelerating HPC Workflows Through Intelligent Data Management
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
The next frontier in AI advancement isn’t just about algorithms—it’s about unlocking the wealth of hidden insights trapped within millions of files in HPC environments. While organizations focus on model architectures, the true bottleneck often lies in discovering and preparing relevant data buried in vast storage systems.
This presentation, featuring MetadataHub and a live demonstration, will reveal how intelligent metadata extraction and management transforms unstructured data into AI-ready assets by:
  • Uncovering Hidden Context: Live metadata extraction demonstrating how MetadataHubcaptures content and contextual value, revealing unexpected connections between research datasets and enabling new AI training opportunities that would otherwise remain hidden.
  • Automating Data Discovery: Demonstrating how MetadataHub automates metadata tagging to identify valuable training data across petabyte-scale storage, reducing data preparation time by up to 90%.
  • Enhancing Model Quality: Exploring how rich metadata captured by MetadataHub improves AI model performance by providing better context and enabling more relevant training data selection.
  • Scaling Efficiently: Showcasing metadata-driven automation with MetadataHub that optimizes data pipeline efficiency and resource utilization, including GPU/CPU performance, across HPC environments.
The session will highlight a real-world success story from the Zuse Institute Berlin, where MetadataHub unlocked 200 PB of previously underutilized research data for cutting-edge Generative AI applications. A 15-minute live demonstration will guide attendees through their journey—from data discovery to AI-ready datasets—highlighting practical challenges and solutions.
Attendees will leave with actionable strategies for implementing metadata-driven approaches in their own HPC workflows. By showcasing MetadataHub’s ability to extract content and contextual value, this session will demonstrate how metadata transforms unstructured data into a strategic advantage, accelerating AI initiatives and driving HPC innovation.
Speakers
Wednesday May 21, 2025 4:30pm - 5:00pm MDT
Room 206
 
Thursday, May 22
 

8:15am MDT

Decoding Brain Tumors with High-Performance Computing
Thursday May 22, 2025 8:15am - 8:45am MDT
Modern single-cell and single-nucleus RNA sequencing allow us to profile every cell within a brain tumor, uncovering the diverse lineages and cell signals that drive growth and therapy resistance. However, each experiment can produce terabytes of raw reads and millions of barcodes, demanding significant CPU, GPU, and memory resources – far beyond the limits of a laptop. This talk will show how high-performance computing (HPC) systems transform that data deluge into biological insight.

I will walk through an end-to-end analysis pipeline that pairs the Cell Ranger aligner with an nf-core workflow for efficient, reproducible processing on CPU and GPU nodes. Interactive exploration then transitions to Seurat, where large-memory nodes accelerate dimensionality reduction, clustering, and differential expression analysis and integration of hundreds of thousands of cells. HPC infrastructure also enables RNA velocity calculations, and trajectory analysis that would be impractical on local workstations.

Benchmarks will illustrate how parallel job arrays and optimized space management can cut runtimes from days to hours while lowering costs. My goal is to provide researchers and students with a clear roadmap for harnessing supercomputers to advance neuro-oncology and other data-intensive areas of life science.
Speakers
JG

Jesus Garcia Garcia

University of Colorado Boulder
Thursday May 22, 2025 8:15am - 8:45am MDT
Room 205

8:15am MDT

Fuzzball: new developments in HPC container orchestration
Thursday May 22, 2025 8:15am - 8:45am MDT
Fuzzball transforms your on-premises or cloud environment into a user-friendly, manageable HPC cluster. In this talk, I’ll share exciting updates from the past year. Fuzzball is now generally available (GA) for on-prem installations and is also offered as a tech preview in the AWS Marketplace. This means you can try Fuzzball in your AWS account and deploy it directly on your on-prem cluster. We’ve also introduced Fuzzball Federate as a tech preview, enabling you to manage multiple Fuzzball clusters through a single console and unified user interface. Additionally, Fuzzball now includes a built-in workflow catalog, featuring CIQ-certified examples of popular applications in an easy-to-use format.
Thursday May 22, 2025 8:15am - 8:45am MDT
Room 207

10:15am MDT

AI4WY: Advancing AI and Scientific Discovery through HPC Infrastructure and Collaborations in the Rocky Mountain Region
Thursday May 22, 2025 10:15am - 10:45am MDT
AI4WY is an NSF MRI-supported project seeking to build regional partnerships to transform the research landscape by acquiring a state-of-the-art high-performance computing (HPC) system. Led by the University of Wyoming in collaboration with Colorado State University and the Rocky Mountain Advanced Computing Consortium (RMACC), the AI4WY cluster will feature NVIDIA Grace Hopper Superchips for empowering AI-driven research and big data modeling across key domains such as environment, agriculture, society, and energy. In this presentation, we will provide an update on the system acquisition, expanding HPC access to RMACC through the NSF ACCESS program, and plans for fostering regional collaboration.
Speakers
Thursday May 22, 2025 10:15am - 10:45am MDT
Room 204

10:15am MDT

Cross-Institutional Data Collaboration: Breaking Silos in HPC Research
Thursday May 22, 2025 10:15am - 10:45am MDT
High-performance computing (HPC) research thrives on collaboration, yet institutional data silos often hinder progress. This extends beyond the storage hardware itself to where data is being siloed in departments and institutions alike. Accelerating scientific progress and innovation requires enabling secure data discovery and sharing across not only institutions, but scientific disciplines as well. Federated access models, controlled permissions, and distributed compute environments enable seamless yet secure collaboration. By facilitating data discovery across disciplines and optimizing shared infrastructure, organizations can break down barriers, enhance research efficiency, and drive cross-disciplinary insights that push the boundaries of scientific advancement.
Speakers
Thursday May 22, 2025 10:15am - 10:45am MDT
Room 206

10:15am MDT

Expanding Access to AI Research: An Overview of NAIRR
Thursday May 22, 2025 10:15am - 10:45am MDT
The National Artificial Intelligence Research Resource (NAIRR) is a federal initiative aimed at providing researchers with greater access to advanced AI tools, datasets, and computing infrastructure. By connecting academic institutions, national labs, and government agencies, NAIRR is building a shared ecosystem to support AI-driven discovery across scientific disciplines. This talk will highlight the goals of the NAIRR pilot, outline its current offerings, and explore how institutions in the RMACC community can engage with and benefit from this growing national effort.
Speakers
Thursday May 22, 2025 10:15am - 10:45am MDT
Wolf Law Courtroom

10:15am MDT

Globus and Compliance
Thursday May 22, 2025 10:15am - 10:45am MDT
With the recent changes to the NIH Genomic Data Sharing Policy, more focus is being placed on compliance today. Organizations are looking for solutions to meet these new requirements. In this session we will discuss how Globus data management services allow users to confidently work with  controlled-access data. We will cover all the product features that address managing controlled-access data to enable compliance with NIST SP 800-171. We will demonstrate how with High Assurance collections the service meets these new requirements.
Speakers
Thursday May 22, 2025 10:15am - 10:45am MDT
Room 207

10:15am MDT

The Evolution of Colorado’s Quantum Ecosystem
Thursday May 22, 2025 10:15am - 10:45am MDT
 This presentation explores key milestones in the Colorado quantum ecosystem’s growth, including the establishment of anchor institutions like JILA and NIST, the role of state and federal policy, and the rise of quantum-focused companies across sensing, computing, and communication. We also examine how Colorado’s collaborative culture, talent pipeline, and public-private partnerships have created a fertile ground for quantum innovation. Looking ahead, the presentation highlights the challenges and opportunities that will shape the next phase of Colorado’s quantum leadership.
Speakers
Thursday May 22, 2025 10:15am - 10:45am MDT
Room 205

11:00am MDT

AMD Roadmap and Technology Update
Thursday May 22, 2025 11:00am - 12:00pm MDT
This presentation provides a comprehensive overview of AMD's current and future technology roadmap, highlighting key innovations, product developments, and strategic direction across its CPU, GPU, and APU portfolios.
Speakers
Thursday May 22, 2025 11:00am - 12:00pm MDT
Room 204
 
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