Quantum computers (QC) can significantly enhance high-performance computing (HPC) as accelerators with unique capabilities for solving challenging chemistry, materials science, and optimization problems. Hybrid HPC+QC system offers unique advantages that neither classical nor quantum simulations can achieve independently. Our collaboration between IQM, a leading quantum hardware company, and a premier HPC center has demonstrated practical integration of quantum and classical resources. We present the details of our technical implementation, including hardware and software requirements, networking, and selection of the appropriate space to house the quantum computer, as well as initial scientific results coming out of that collaboration. We also discuss how QC can be integrated with minimal disruption into HPC workflows and the benefits of on-prem QC.